Article
The influence of the CYP3A4*22 polymorphism on serum concentration of quetiapine in psychiatric patients.
Journal of clinical psychopharmacology - 1 Apr 2014
van der Weide Karen, van der Weide Jan
Abstract excerpt
BACKGROUND: Besides dietary, hormonal, or pathological factors, mutations in cytochrome P450 enzymes are thought to be responsible for the interindividual differences in serum concentrations of cytochrome P450 (CYP450)-dependent drugs. Cytochrome P450 3A4 (CYP3A4) is involved in the metabolism of...
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