Is there an association between advanced paternal age and endophenotype deficit levels in schizophrenia?

doi:10.1371/journal.pone.0088379

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Article

Is there an association between advanced paternal age and endophenotype deficit levels in schizophrenia?

PloS one - 1 Jan 2014

Tsuang Debby, Esterberg Michelle, Braff David, Calkins Monica, Cadenhead Kristin, Dobie Dorcas, Freedman Robert, Green Michael F, Greenwood Tiffany, Gur Raquel, Gur Ruben, Horan William, Lazzeroni Laura C, Light Gregory A, Millard Steven P, Olincy Ann, Nuechterlein Keith, Seidman Larry, Siever Larry, Silverman Jeremy, Stone William, Sprock Joyce, Sugar Catherine, Swerdlow Neal, Tsuang Ming, Turetsky Bruce, Radant Allen

Abstract excerpt

The children of older fathers have increased risks of developing schizophrenia spectrum disorders, and among those who develop these disorders, those with older fathers present with more severe clinical symptoms. However, the influence of advanced paternal age on other important domains related to schizophrenia, such as quantitative endophenotype deficit levels, remains unknown. This study investigated the...

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Identifiers

PMID: 24523888
DOI: 10.1371/journal.pone.0088379
PMCID: PMC3921166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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