Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.

Cancer - 15 May 2014

Jackson Sarah A, Davis Andrew A, Li Jun, Yi Nengjun, McCormick Shelley R, Grant Carly, Fallen Taya, Crawford Beth, Loranger Kate, Litton Jennifer, Arun Banu, Vande Wydeven Kimberly, Sidani Amer, Farmer Katie, Sanders Merideth, Hoskins Kent, Nussbaum Robert, Esserman Laura, Garber Judy E, Kaklamani Virginia G

Abstract excerpt

BACKGROUND: Large rearrangements in BRCA1 and BRCA2 occur in a small percentage (< 1%) of patients tested for hereditary breast (BC) and ovarian cancer. It is unclear what factors predict BRACAnalysis Large Rearrangement Test (BART) positivity. METHODS: Data from 6 centers were included in this analysis. Individuals with negative Comprehensive BRACAnalysis tested for BART were included. RESULTS: From 1300...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma, Mucinous
Share to Area Under Curve

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Ductal, Breast

Share to Carcinoma, Intraductal, Noninfiltrating

Share to Carcinoma, Lobular

Share to Caribbean Region

Share to Hispanic or Latino

Source

Identifiers

PMID: 24522996
DOI: 10.1002/cncr.28577

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.PMID 24522996Read ↗

Assessment of individuals with BRCA1 and BRCA2 large rearrangements in high-risk breast and ovarian cancer families.Semantic proximity Read ↗

Outcomes of large panel genetic evaluation of breast cancer patients in a community-based cancer institute.Semantic proximity Read ↗

Expanding BRCA1/BRCA2 genomic diversity in the Caribbean: insights from the first national cohort in the Dominican RepublicSemantic proximity Read ↗

Clinical significance of large rearrangements in BRCA1 and BRCA2.Semantic proximity Read ↗

Large genomic rearrangements in the familial breast and ovarian cancer gene BRCA1 are associated with an increased frequency of high risk features.Semantic proximity Read ↗

Whole exome sequencing and replication for breast cancer among Hispanic/Latino women identifies<i>FANCM</i>as a susceptibility gene for estrogen-receptor-negative breast cancerSemantic proximity Read ↗

Absence of genomic BRCA1 and BRCA2 rearrangements in Ashkenazi breast and ovarian cancer families.Semantic proximity Read ↗

Breast cancer surveillance following ovarian cancer in BRCA mutation carriers.Semantic proximity Read ↗

Genetic and clinical characterization of BRCA-associated Hereditary Breast and Ovarian Cancer in Navarra (Spain)Semantic proximity Read ↗

Racial and Ethnic Differences in Multigene Hereditary Cancer Panel Test Results for Women With Breast Cancer.Semantic proximity Read ↗

The contribution of LARGE genomic rearrangements of BRCA1 and BRCA2 gene mutations in breast and ovarian cancer families in a clinical cohortSemantic proximity Read ↗

Which individuals undergoing BRACAnalysis need BART testing?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.