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Article

Interactive effect of MTHFR and ADRA2A gene polymorphisms on pathogenesis of schizophrenia.

Neuro endocrinology letters - 1 Jan 2013

Lochman Jan, Plesník Jiří, Janout Vladimír, Povová Jana, Míšek Ivan, Dvořáková Dagmar, Šerý Omar

Abstract excerpt

OBJECTIVES: Increasing evidences support the importance of epigenetic control in schizophrenia pathogenesis. One of the enzymes involved in DNA methylation process through homocysteine metabolism is methylenetetrahydrofolate reductase (MTHFR). The most extensively studied variant in the MTHFR gen...

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Share to Epigenesis, Genetic
Share to Genetic Predisposition to Disease
Share to Methylenetetrahydrofolate Reductase (NADPH2)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Receptors, Adrenergic, alpha-2

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Source

Identifiers

PMID: 24522021

Genes

MTHFR
COMT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24522021-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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