Article
Epstein-Barr virus and human papillomavirus infections and genotype distribution in head and neck cancers.
PloS one - 1 Jan 2014
Deng Zeyi, Uehara Takayuki, Maeda Hiroyuki, Hasegawa Masahiro, Matayoshi Sen, Kiyuna Asanori, Agena Shinya, Pan Xiaoli, Zhang Chunlin, Yamashita Yukashi, Xie Minqiang, Suzuki Mikio
Abstract excerpt
OBJECTIVE: To investigate the prevalence, genotypes, and prognostic values of Epstein-Barr virus (EBV) and human papillomavirus (HPV) infections in Japanese patients with different types of head and neck cancer (HNC). METHODS AND MATERIALS: HPV and EBV DNA, EBV genotypes and LMP-1 variants, and HPV mRNA expression were detected by PCR from fresh-frozen HNC samples. HPV genotypes were determined by direct...
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