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Joint effects of known type 2 diabetes susceptibility loci in genome-wide association study of Singapore Chinese: the Singapore Chinese health study.

PloS one - 1 Jan 2014

Chen Zhanghua, Pereira Mark A, Seielstad Mark, Koh Woon-Puay, Tai E Shyong, Teo Yik-Ying, Liu Jianjun, Hsu Chris, Wang Renwei, Odegaard Andrew O, Thyagarajan Bharat, Koratkar Revati, Yuan Jian-Min, Gross Myron D, Stram Daniel O

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWAS) have identified genetic factors in type 2 diabetes (T2D), mostly among individuals of European ancestry. We tested whether previously identified T2D-associated single nucleotide polymorphisms (SNPs) replicate and whether SNPs in regions near known T2D SNPs were associated with T2D within the Singapore Chinese Health Study. METHODS: 2338 cases and 2339 T2D...

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Identifiers

PMID: 24520337
DOI: 10.1371/journal.pone.0087762
PMCID: PMC3919750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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