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Article

The emerging role of mTOR signalling in antibacterial immunity

11 Feb 2014

Abstract excerpt

Mammalian target of rapamycin (mTOR) is a central regulator of cellular metabolic homeostasis that is highly conserved in evolution. Recent evidence has revealed the existence of a complex interplay between mTOR signalling and immunity. We review here the emerging role of mTOR signalling in the regulation of Toll-like receptor-dependent innate responses and in the activation of T cells and antigen-presenting...

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PMID: 24518980
DOI: 10.1038/icb.2014.3

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