Article
Genotypic determination of HIV tropism in a cohort of patients perinatally infected with HIV-1 and exposed to antiretroviral therapy.
HIV clinical trials - 1 Jan 2000
Di Biagio Antonio, Parisini Andrea, Bruzzone Bianca, Prinapori Roberta, Lauriola Marinella, Paolucci Stefania, Signori Alessio, Barresi Renata, Icardi Giancarlo, Calderisi Silvia, Meini Genny, Dentone Chiara, Cenderello Giovanni, Guerra Michele, Maccabruni Anna, Rusconi Stefano, Viscoli Claudio
Abstract excerpt
The aim of this study was to determine the coreceptor tropism by performing genotypic HIV-1 tropism testing in a cohort of patients perinatally infected with HIV-1 and exposed to antiretroviral therapy. Genotypic coreceptor tropism was determined in patients with HIV-1 RNA<100 copies/mL using PBMC samples by gp120 V3 sequencing followed by geno2pheno interpretation (set at a false positive rate [FPR] of 20%) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.