Article
HIV-1 tropism: a comparison between RNA and proviral DNA in routine clinical samples from Chilean patients.
Virology journal - 28 Oct 2013
Ferrer Pablo, Montecinos Luisa, Tello Mario, Tordecilla Rocio, Rodríguez Consuelo, Ferrés Marcela, Pérez Carlos M, Beltrán Carlos, Guzmán Maria A, Afani Alejandro
Abstract excerpt
BACKGROUND: HIV in Chile has a notification rate of 0.01%. Coreceptor antagonists are a family of antiretroviral drugs that are used with the prior knowledge of patients HIV-1 tropism. Viral RNA-based tropism detection requires a plasma viral load ≥1000 copies/mL, while proviral DNA-based detection can be performed regardless of plasma viral load. This test is useful in patients with low or undetectable viral...
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