Metadata Standard and Data Exchange Specifications to Describe, Model, and Integrate Complex and Diverse High-Throughput Screening Data from the Library of Integrated Network-based Cellular Signatures (LINCS).

doi:10.1177/1087057114522514

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Metadata Standard and Data Exchange Specifications to Describe, Model, and Integrate Complex and Diverse High-Throughput Screening Data from the Library of Integrated Network-based Cellular Signatures (LINCS).

Journal of biomolecular screening - 1 Jun 2014

Vempati Uma D, Chung Caty, Mader Chris, Koleti Amar, Datar Nakul, Vidović Dušica, Wrobel David, Erickson Sean, Muhlich Jeremy L, Berriz Gabriel, Benes Cyril H, Subramanian Aravind, Pillai Ajay, Shamu Caroline E, Schürer Stephan C

Abstract excerpt

The National Institutes of Health Library of Integrated Network-based Cellular Signatures (LINCS) program is generating extensive multidimensional data sets, including biochemical, genome-wide transcriptional, and phenotypic cellular response signatures to a variety of small-molecule and genetic perturbations with the goal of creating a sustainable, widely applicable, and readily accessible systems biology...

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Metadata Standard and Data Exchange Specifications to Describe, Model, and Integrate Complex and Diverse High-Throughput Screening Data from the Library of Integrated Network-based Cellular Signatures (LINCS).

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