Correlation of cytomorphology and molecular findings in EGFR+, KRAS+, and ALK+ lung carcinomas.

doi:10.1309/AJCPHF51LSPCAXTA

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Article

Correlation of cytomorphology and molecular findings in EGFR+, KRAS+, and ALK+ lung carcinomas.

American journal of clinical pathology - 1 Mar 2014

Li Zaibo, Dacic Sanja, Pantanowitz Liron, Khalbuss Walid E, Nikiforova Marina N, Monaco Sara E

Abstract excerpt

OBJECTIVES: There is increasing emphasis on the subclassification of non-small cell lung carcinomas (NSCLCs) and molecular features to guide treatment. Histologic studies have suggested some morphologic features predominating in tumors. Our aim was to determine if mutated cases had distinct cytomorphology. METHODS: A retrospective study was designed to retrieve all cytopathology cases of NSCLC that had mutation...

Topics

Adult
Aged
Aged, 80 and over
Anaplastic Lymphoma Kinase
Carcinoma, Non-Small-Cell Lung
ErbB Receptors
Humans
Lung Neoplasms
Male
Middle Aged
Mutation
Receptor Protein-Tyrosine Kinases
ras Proteins

Source

Open in PubMed

Identifiers

PMID: 24515771
DOI: 10.1309/AJCPHF51LSPCAXTA

Genes

ALK
EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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