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Article

Cytomorphological correlates of epidermal growth factor receptor mutations in lung carcinoma.

Diagnostic cytopathology - 1 May 2007

Brachtel Elena F, Iafrate A John, Mark Eugene J, Deshpande Vikram

Abstract excerpt

The initial diagnosis of lung carcinoma is frequently made by fine-needle aspiration biopsy. Novel therapeutic strategies of this disease include tyrosine kinase inhibitors (TKI), such as gefitinib (Iressa) or erlotinib (Tarceva), which target the kinase domain of epidermal growth factor receptor (EGFR). Somatic mutations of this region have been shown to predict a therapeutic response of lung carcinomas to TKI....

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Identifiers

PMID: 17427221
DOI: 10.1002/dc.20617

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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