Article
Association between copy number variation losses and alcohol dependence across African American and European American ethnic groups.
Alcoholism, clinical and experimental research - 1 May 2014
Ulloa Alvaro E, Chen Jiayu, Vergara Victor M, Calhoun Vince, Liu Jingyu
Abstract excerpt
BACKGROUND: Copy number variations (CNVs) are structural genetic mutations consisting of segmental gains or losses in DNA sequence. Although CNVs contribute substantially to genomic variation, few genetic and imaging studies report association of CNVs with alcohol dependence (AD). Our purpose is to find evidence of this association across ethnic populations and genders. This work is the first AD-CNV study across...
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