Article
Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence.
Alcoholism, clinical and experimental research - 1 Sept 2012
Lin Peng, Hartz Sarah M, Wang Jen-Chyong, Agrawal Arpana, Zhang Tian-Xiao, McKenna Nicholas, Bucholz Kathleen, Brooks Andrew I, Tischfield Jay A, Edenberg Howard J, Hesselbrock Victor M, Kramer John R, Kuperman Samuel, Schuckit Marc A, Goate Alison M, Bierut Laura J, Rice John P
Abstract excerpt
BACKGROUND: Excessive alcohol use is the third leading cause of preventable death and is highly correlated with alcohol dependence, a heritable phenotype. Many genetic factors for alcohol dependence have been found, but many remain unknown. In search of additional genetic factors, we examined the association between Diagnostic and StatisticalManual of Mental Disorders, Fourth Edition (DSM-IV) alcohol dependence...
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