Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TDP-43 in ALS: stay on target…almost there.

Neuron - 5 Feb 2014

Jovičić Ana, Gitler Aaron D

Abstract excerpt

ALS is associated with RNA processing impairments involving the RNA-binding protein TDP-43. Pioneering a novel RNA beacon to illuminate RNA trafficking in neurons, Alami et al. (2014) discover a cytoplasmic function for TDP-43, suggesting a new disease mechanism.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis
Share to DNA-Binding Proteins
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurons

Source

Open in PubMed Open full text

Identifiers

PMID: 24507183
DOI: 10.1016/j.neuron.2014.01.034
PMCID: PMC3962496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TDP-43 in ALS: stay on target…almost there.PMID 24507183Read ↗

Decoding TDP-43: the molecular chameleon of neurodegenerative diseasesSemantic proximity Read ↗

Understanding age-related pathologic changes in TDP-43 functions and the consequence on RNA splicing and signalling in health and diseaseSemantic proximity Read ↗

Altered TDP-43 Structure and Function: Key Insights into Aberrant RNA, Mitochondrial, and Cellular and Systemic Metabolism in Amyotrophic Lateral SclerosisSemantic proximity Read ↗

TDP-43 proteinopathies: a new wave of neurodegenerative diseasesSemantic proximity Read ↗

Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD.Semantic proximity Read ↗

TDP-43 directly inhibits RNA accumulation in neurites through modulation of RNA stabilitySemantic proximity Read ↗

TDP-43: a DNA and RNA binding protein with roles in neurodegenerative diseases.Semantic proximity Read ↗

Molecular Dissection of TDP-43 as a Leading Cause of ALS/FTLDSemantic proximity Read ↗

Connecting TDP-43 Pathology with Neuropathy.Semantic proximity Read ↗

Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.Semantic proximity Read ↗

TDP-43—The key to understanding amyotrophic lateral sclerosisSemantic proximity Read ↗

Rethinking ALS: the FUS about TDP-43.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.