Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TDP-43: a DNA and RNA binding protein with roles in neurodegenerative diseases.

The international journal of biochemistry & cell biology - 1 Oct 2010

Warraich Sadaf T, Yang Shu, Nicholson Garth A, Blair Ian P

Abstract excerpt

Transactive response DNA binding protein 43 kDa (TDP-43) is a DNA and RNA binding protein involved in RNA processing and with structural resemblance to heterogeneous ribonucleoproteins (hnRNPs). TDP-43 serves multiple functions with roles in transcriptional regulation, pre-mRNA splicing and trans...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Progression
Share to Embryonic Development
Share to Inclusion Bodies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to RNA-Binding Proteins

Share to RNA Processing, Post-Transcriptional

Share to RNA Splicing

Share to TDP-43 Proteinopathies

Share to Transcriptional Activation

Source

Identifiers

PMID: 20601083
DOI: 10.1016/j.biocel.2010.06.016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20601083-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TDP-43: a DNA and RNA binding protein with roles in neurodegenerative diseases.PMID 20601083Read ↗

TDP-43 proteinopathies: a new wave of neurodegenerative diseasesSemantic proximity Read ↗

Decoding TDP-43: the molecular chameleon of neurodegenerative diseasesSemantic proximity Read ↗

Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases.Semantic proximity Read ↗

Connecting TDP-43 Pathology with Neuropathy.Semantic proximity Read ↗

Understanding age-related pathologic changes in TDP-43 functions and the consequence on RNA splicing and signalling in health and diseaseSemantic proximity Read ↗

The role of TDP-43 in the pathogenesis of ALS and FTLDSemantic proximity Read ↗

TDP-43 post-translational modifications in health and diseaseSemantic proximity Read ↗

TDP-43 Epigenetic Facets and Their Neurodegenerative ImplicationsSemantic proximity Read ↗

Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders.Semantic proximity Read ↗

Multiple roles of TDP-43 in gene expression, splicing regulation, and human diseaseSemantic proximity Read ↗

TDP-43: a novel neurodegenerative proteinopathySemantic proximity Read ↗

Review: Transactive response DNA-binding protein 43 (TDP-43): mechanisms of neurodegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.