Article
Distinct domains within the human cytomegalovirus U(L)26 protein are important for wildtype viral replication and virion stability.
PloS one - 1 Jan 2014
Mathers Chun, Spencer Cody M, Munger Joshua
Abstract excerpt
The human cytomegalovirus (HCMV) U(L)26 gene encodes a virion protein that is important for high titer viral replication. To identify specific domains within the U(L)26 protein that contribute to viral infection, we created a panel of site-directed U(L)26 mutant viruses and assessed their impact on phenotypes attributed to U(L)26. We find that the C-terminal 38 amino acids of the U(L)26 protein are absolutely...
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