Article
The contribution of interleukin-8 genotypes and expression to nasopharyngeal cancer susceptibility in Taiwan.
Medicine - 1 Sept 2018
Huang Chung-Yu, Chang Wen-Shin, Tsai Chia-Wen, Hsia Te-Chun, Shen Te-Chun, Bau Da-Tian, Shui Hao-Ai
Abstract excerpt
The incidence rate of nasopharyngeal cancer (nasopharyngeal carcinoma [NPC]) is much higher in Southeast Asia than in western countries. Interleukin-8 (IL-8), a chemokine produced by macrophages, epithelial cells, airway smooth muscle cells, and endothelial cells, is an important immuno-mediator in the development and progression of many types of cancer. Genetic variations in IL-8 have been associated with the...
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