Article
A novel approach for HLA-A typing in formalin-fixed paraffin-embedded-derived DNA.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2014
Villabona Lisa, Leon Rodriguez Daniel A, Andersson Emilia K, Seliger Barbara, Dalianis Tina, Masucci Giuseppe V
Abstract excerpt
The aim of this study was to establish a novel approach for human leukocyte antigen (HLA)-typing from formalin-fixed paraffin-embedded-derived DNA. HLAs can be a prognostic factor in cancer and have an extensive polymorphism. This polymorphism is predominantly restricted to exons, which encode the peptide-binding domain of the protein. Formalin-fixed paraffin-embedded material is routinely collected in the clinic...
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