Article
Genotyping of human leukocyte antigen (HLA) ancestral haplotypes as prognostic marker in cancer using PCR analysis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014
Villabona Lisa, Andersson Emilia, Marchesi Maddalena, Masucci Giuseppe V
Abstract excerpt
The major histocompatibility complex (MHC) comprises a set of genes that are essential to immunity and surveillance against neoplastic transformation. MHC antigens not only regulate antitumor immune responses in experimental animal models but also directly correlate with survival and prognosis of patients with various types of cancers. Effective recognition of tumor cells by effector T cells may be affected by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
