Article
Bmp suppression in mangrove killifish embryos causes a split in the body axis.
PloS one - 1 Jan 2014
Mourabit Sulayman, Moles Michael W, Smith Emma, van Aerle Ronny, Kudoh Tetsuhiro
Abstract excerpt
Bone morphogenetic proteins (Bmp) are major players in the formation of the vertebrate body plan due to their crucial role in patterning of the dorsal-ventral (DV) axis. Despite the highly conserved nature of Bmp signalling in vertebrates, the consequences of changing this pathway can be species-specific. Here, we report that Bmp plays an important role in epiboly, yolk syncytial layer (YSL) movements, and...
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