Article
Super Spy variants implicate flexibility in chaperone action.
eLife - 1 Jan 2014
Quan Shu, Wang Lili, Petrotchenko Evgeniy V, Makepeace Karl At, Horowitz Scott, Yang Jianyi, Zhang Yang, Borchers Christoph H, Bardwell James Ca
Abstract excerpt
Experimental study of the role of disorder in protein function is challenging. It has been proposed that proteins utilize disordered regions in the adaptive recognition of their various binding partners. However apart from a few exceptions, defining the importance of disorder in promiscuous binding interactions has proven to be difficult. In this paper, we have utilized a genetic selection that links protein...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.