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Integrin traffic – the update

1 Jan 2015

Abstract excerpt

Integrins are a family of transmembrane cell surface molecules that constitute the principal adhesion receptors for the extracellular matrix (ECM) and are indispensable for the existence of multicellular organisms. In vertebrates, 24 different integrin heterodimers exist with differing substrate specificity and tissue expression. Integrin-extracellular-ligand interaction provides a physical anchor for the cell...

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PMID: 25663697
DOI: 10.1242/jcs.161653

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