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Article

Staging of biliary atresia at diagnosis by molecular profiling of the liver

13 May 2010

Abstract excerpt

BACKGROUND: Young age at portoenterostomy has been linked to improved outcome in biliary atresia, but pre-existing biological factors may influence the rate of disease progression. In this study, we aimed to determine whether molecular profiling of the liver identifies stages of disease at diagnosis. METHODS: We examined liver biopsies from 47 infants with biliary atresia enrolled in a prospective observational...

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PMID: 20465800
DOI: 10.1186/gm154

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