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Article

Integrative genomics identifies candidate microRNAs for pathogenesis of experimental biliary atresia

20 Oct 2013

Abstract excerpt

BACKGROUND: Biliary atresia is a fibroinflammatory obstruction of extrahepatic bile duct that leads to end-stage liver disease in children. Despite advances in understanding the pathogenesis of biliary atresia, very little is known about the role of microRNAs (miRNAs) in onset and progression of the disease. In this study, we aimed to investigate the entire biliary transcriptome to identify miRNAs with potential...

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PMID: 24138927
DOI: 10.1186/1752-0509-7-104

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