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A tumor of the uterine cervix with a complex histology in a Peutz-Jeghers syndrome patient with genomic deletion of the STK11 exon 1 region.

Future oncology (London, England) - 1 Feb 2014

Kobayashi Yusuke, Masuda Kenta, Kimura Tokuhiro, Nomura Hiroyuki, Hirasawa Akira, Banno Kouji, Susumu Nobuyuki, Sugano Kokichi, Aoki Daisuke

Abstract excerpt

Patients with Peutz-Jeghers syndrome (PJS) have a risk of complicating malignant tumors, including cancer of the uterine cervix. Mutations in the STK11 gene have been identified as being responsible for PJS. However, the genotype-phenotype correlation in PJS is poorly understood, especially with respect to malignant tumors. Here, we report a detailed analysis of a case of a cervical tumor in a PJS patient showing...

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Identifiers

PMID: 24490603
DOI: 10.2217/fon.13.180

Genes

STK11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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