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Article

A case of Peutz-Jeghers syndrome with breast cancer, bilateral sex cord tumor with annular tubules, and adenoma malignum caused by STK11 gene mutation.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Dec 2009

Clements Aine, Robison Katina, Granai Cornelius, Steinhoff Margaret M, Scalia-Wilbur Jennifer, Moore Richard G

Abstract excerpt

BACKGROUND: Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant disorder, and women with this syndrome are at an increased risk of developing intestinal and extraintestinal malignancies including breast and gynecologic malignancies. This case report presents a patient with PJS with a concom...

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Source

Identifiers

PMID: 19955943
DOI: 10.1111/IGC.0b013e3181ae3f71

Genes

STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19955943-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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A case of Peutz-Jeghers syndrome with breast cancer, bilateral sex cord tumor with annular tubules, and adenoma malignum caused by STK11 gene mutation.PMID 19955943Read ↗

Different phenotypes including gynecological cancer in three female patients with Peutz-Jeghers syndrome and mutations in the STK11 gene.Semantic proximity Read ↗

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Serine/threonine kinase 11 (STK11) associated adnexal tumors: from biology to therapeutic impact.Semantic proximity Read ↗

A tumor of the uterine cervix with a complex histology in a Peutz-Jeghers syndrome patient with genomic deletion of the STK11 exon 1 region.Semantic proximity Read ↗

Aggressive Course of STK11/ FOXL2 -Wildtype Adult Granulosa Cell Tumor in Peutz– Jeghers Syndrome: A Case ReportSemantic proximity Read ↗

A Distinctive Adnexal (Usually Paratubal) Neoplasm Often Associated With Peutz-Jeghers Syndrome and Characterized by STK11 Alterations (STK11 Adnexal Tumor): A Report of 22 Cases.Semantic proximity Read ↗

When Synchronous Mucinous Metaplasia and Neoplasia of the Female Genital Tract and Peutz-Jeghers Syndrome Meet: A Case Report and Literature ReviewsSemantic proximity Read ↗

Somatic mutations in the STK11/LKB1 gene are uncommon in rare gynecological tumor types associated with Peutz-Jegher's syndrome.Semantic proximity Read ↗

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Synchronous mucinous metaplasia and neoplasia of the ovarium and fallopian tube with STK11 and KRAS mutations: a case report.Semantic proximity Read ↗

Sex-Cord Tumor with Annular Tubules with Unusual Morphology in an Infant with Peutz-Jeghers Syndrome.Semantic proximity Read ↗

High cancer risk in Peutz-Jeghers syndrome: a systematic review and surveillance recommendations.Semantic proximity Read ↗

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