Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in the STK11 gene characterize minimal deviation adenocarcinoma of the uterine cervix.

Laboratory investigation; a journal of technical methods and pathology - 1 Jan 2003

Kuragaki Chie, Enomoto Takayuki, Ueno Yuko, Sun Hongbo, Fujita Masami, Nakashima Ryuichi, Ueda Yutaka, Wada Hiroko, Murata Yuji, Toki Toshihiko, Konishi Ikuo, Fujii Shingo

Abstract excerpt

Minimal deviation adenocarcinoma (MDA) is a well-differentiated variant of mucinous adenocarcinoma of the uterine cervix and is found relatively infrequently in the general population. However, MDA is strongly associated with Peutz-Jeghers syndrome (PJS), a rare hereditary autosomal disorder characterized by benign hamartomatous polyposis in the gastrointestinal tract and mucocutaneous pigmentation. A serine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to AMP-Activated Protein Kinase Kinases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Immunohistochemistry

Share to Polymerase Chain Reaction

Share to Polymorphism, Single-Stranded Conformational

Share to Protein Serine-Threonine Kinases

Share to Uterine Neoplasms

Source

Identifiers

PMID: 12533684
DOI: 10.1097/01.lab.0000049821.16698.d0

Genes

STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in the STK11 gene characterize minimal deviation adenocarcinoma of the uterine cervix.PMID 12533684Read ↗

A tumor of the uterine cervix with a complex histology in a Peutz-Jeghers syndrome patient with genomic deletion of the STK11 exon 1 region.Semantic proximity Read ↗

Different phenotypes including gynecological cancer in three female patients with Peutz-Jeghers syndrome and mutations in the STK11 gene.Semantic proximity Read ↗

Somatic mutations in the STK11/LKB1 gene are uncommon in rare gynecological tumor types associated with Peutz-Jegher's syndrome.Semantic proximity Read ↗

Relative frequency and morphology of cancers in STK11 mutation carriers.Semantic proximity Read ↗

STK11 domain XI mutations: candidate genetic drivers leading to the development of dysplastic polyps in Peutz-Jeghers syndrome.Semantic proximity Read ↗

An exploration of genotype-phenotype link between Peutz-Jeghers syndrome and STK11: a review.Semantic proximity Read ↗

Mutational analysis of STK11 gene in ovarian carcinomas.Semantic proximity Read ↗

Malignant STK11 adnexal tumor harboring a somatic mutation in a woman previously diagnosed with mesothelioma, a case reportSemantic proximity Read ↗

Peutz-Jeghers Syndrome: Pathobiology, Pathologic Manifestations, and Suggestions for Recommending Genetic Testing in Pathology Reports.Semantic proximity Read ↗

Close and regular surveillance is key to prevent severe complications for Peutz-Jeghers syndrome patients without gastrointestinal polyps: case report of a novel STK11 mutation (c.471_472delCT) in a Chinese girl.Semantic proximity Read ↗

Clonality analysis suggests that STK11 gene mutations are involved in progression of lobular endocervical glandular hyperplasia (LEGH) to minimal deviation adenocarcinoma (MDA).Semantic proximity Read ↗

A 23-Nucleotide Deletion in STK11 Gene Causes Peutz-Jeghers Syndrome and Malignancy in a Chinese Patient Without a Positive Family History.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.