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Article

Snail contributes to the maintenance of stem cell-like phenotype cells in human pancreatic cancer.

PloS one - 1 Jan 2014

Zhou Wei, Lv Ran, Qi Weilin, Wu Di, Xu Yunyun, Liu Wei, Mou Yiping, Wang Liewei

Abstract excerpt

Snail, a potent repressor of E-cadherin expression, plays a key role in epithelial-to-mesenchymal transition (EMT) in epithelial cancer. Recently, EMT and stemness programs are found linked together. In the current study, the expression of Snail and its contribution to cancer stem cell (CSC) marker expression, invasiveness, self-renewal, clonogenicity, and tumorigenicity of pancreatic cancer cells were studied....

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Source

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Identifiers

PMID: 24489910
DOI: 10.1371/journal.pone.0087409
PMCID: PMC3906155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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