Article

Epithelial and Mesenchymal Pancreatic Cancer Cells Exhibit Different Stem Cell Phenotypes Being Associated with Different Metastatic Propensity

2023-11-16

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is mostly diagnosed at advanced or even metastasized stages limiting patient´s prognosis. Metastasis requires high tumor cell plasticity implying phenotypic switching in response to changing environments. Here, Epithelial-Mesenchymal-Transition (EMT), being associated with the gain of cancer stem cell (CSC) properties, and its reversion are important. Since it is poorly unde...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 4b375229-7e2e-505f-89ba-474ccc454aba
DOI: 10.20944/preprints202311.1083.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Epithelial and Mesenchymal Pancreatic Cancer Cells Exhibit Different Stem Cell Phenotypes Being Associated with Different Metastatic PropensityDOI 10.20944/preprints202311.1083.v1Read

Epithelial and Mesenchymal-like Pancreatic Cancer Cells Exhibit Different Stem Cell Phenotypes Associated with Different Metastatic PropensitiesSemantic proximity Read

Concise Review: Stem Cells in Pancreatic Cancer: From Concept to TranslationSemantic proximity Read

Epithelial-mesenchymal plasticity—engaging stemness in an interplay of phenotypesSemantic proximity Read

Pancreatic cancer stem cells – update and future perspectivesSemantic proximity Read

Holoclone Forming Cells from Pancreatic Cancer Cells Enrich Tumor Initiating Cells and Represent a Novel Model for Study of Cancer Stem CellsSemantic proximity Read

Establishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model system.Semantic proximity Read

Pancreatic cancer stem cells: new insights and perspectivesSemantic proximity Read

The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1—A Useful Model to Study Clonal Heterogeneity and EMT Subtype ShiftingSemantic proximity Read

Pancreatic cancer stem cell markers and exosomes - the incentive pushSemantic proximity Read

Pancreatic tumor microenvironment confers highly malignant properties on pancreatic cancer cellsSemantic proximity Read

Establishment and Characterization of Paired Primary Cultures of Human Pancreatic Cancer Cells and Stellate Cells Derived from the Same Tumor.Semantic proximity Read

Co-Expression of Cancer Stem Cell Markers Corresponds to a Pro-Tumorigenic Expression Profile in Pancreatic AdenocarcinomaSemantic proximity Read