Article
The sirtuin class of histone deacetylases: Regulation and roles in lipid metabolism
1 Feb 2014
Abstract excerpt
After the completion of the human genome sequence and that from many other organisms, last decade has witnessed a spectacular gain of knowledge on gene functions. These studies provided new insights on the roles of genes in physiology and disease. Nonetheless, the availability of genetically modified models and of "omics" technologies such as next generation sequencing unveiled clear evidences on epigenetic...
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