Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting <scp>DNA</scp> damage response in cancer therapy

31 Jan 2014

Abstract excerpt

Cancer chemotherapy and radiotherapy are designed to kill cancer cells mostly by inducing DNA damage. DNA damage is normally recognized and repaired by the intrinsic DNA damage response machinery. If the damaged lesions are successfully repaired, the cells will survive. In order to specifically and effectively kill cancer cells by therapies that induce DNA damage, it is important to take advantage of specific...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer therapeutics and mechanisms
Share to DNA Repair Mechanisms
Share to PARP inhibition in cancer therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24484288
DOI: 10.1111/cas.12366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting <scp>DNA</scp> damage response in cancer therapyPMID 24484288Read ↗

Inhibiting the<scp>DNA</scp>damage response as a therapeutic manoeuvre in cancerSemantic proximity Read ↗

Inhibition of DNA Repair in Cancer Therapy: Toward a Multi-Target ApproachSemantic proximity Read ↗

Targeting DNA repair pathways: mechanisms and potential applications in cancer therapySemantic proximity Read ↗

Targeting DNA repair pathway in cancer: Mechanisms and clinical applicationSemantic proximity Read ↗

Repurposing DNA repair factors to eradicate tumor cells upon radiotherapySemantic proximity Read ↗

DNA Damage and Its Role in Cancer Therapeutics.Semantic proximity Read ↗

DNA damage response, genetic instability and cancer: From mechanistic insights to personalized treatmentSemantic proximity Read ↗

Targeting DNA damage response pathways in cancer.Semantic proximity Read ↗

Targeting the DNA Damage Response for Cancer TherapySemantic proximity Read ↗

DNA Damage Response in Cancer Therapy and Resistance: Challenges and OpportunitiesSemantic proximity Read ↗

Therapeutic Targeting of DNA Damage Response in CancerSemantic proximity Read ↗

Harnessing DNA Double-Strand Break Repair for Cancer TreatmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.