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Article

C242T polymorphism in CYBA gene (p22phox) and risk of coronary artery disease in a population of Caucasian Italians.

Disease markers - 1 Jan 2006

Nasti Sabina, Spallarossa Paolo, Altieri Paola, Garibaldi Silvano, Fabbi Patrizia, Polito Luisa, Bacino Luca, Brunelli Michele, Brunelli Claudio, Barsotti Antonio, Ghigliotti Giorgio

Abstract excerpt

BACKGROUND: specific polymorphisms of genes regulating intracellular redox balance and oxidative stress are related to atherogenesis. Some studies have identified a relationship between progression of atherosclerosis and C242T mutation in CYBA gene coding for p22phox, a subunit of the NADH/NADPH oxidase system. DESIGN: we investigated whether the C242T nucleotide transition is associated with the presence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 16788250
DOI: 10.1155/2006/458587
PMCID: PMC3851654

Genes

CAD
CYBA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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C242T polymorphism in CYBA gene (p22phox) and risk of coronary artery disease in a population of Caucasian Italians.PMID 16788250Read ↗

Relationship of the p22phox (CYBA) gene polymorphism C242T with risk of coronary artery disease: a meta-analysis.Semantic proximity Read ↗

CYBA gene variants as biomarkers for coronary artery disease.Semantic proximity Read ↗

Polymorphism of the NADH/NADPH Oxidase <i>p22 phox</i> Gene in Patients With Coronary Artery DiseaseSemantic proximity Read ↗

Insight into the role of CYBA A640G and C242T gene variants and coronary heart disease risk. A case-control study.Semantic proximity Read ↗

The 242T variant of the CYBA gene polymorphism increases the risk of coronary artery disease associated with cigarette smoking and hypercholesterolemia.Semantic proximity Read ↗

Polymorphisms of C242T and A640G in CYBA gene and the risk of coronary artery disease: a meta-analysis.Semantic proximity Read ↗

The A640G polymorphism in the NAD(P)H oxidase p22phox gene (CYBA) is associated with risk reduction of coronary heart disease: a meta-analysis.Semantic proximity Read ↗

The -930A>G polymorphism of the CYBA gene is associated with premature coronary artery disease. A case-control study and gene-risk factors interactions.Semantic proximity Read ↗

NADH/NADPH oxidase <i>p22</i><i>phox</i> C242T polymorphism and coronary artery disease in the Australian populationSemantic proximity Read ↗

The C242T polymorphism of the NAD(P)H oxidase p22phox subunit is associated with an enhanced risk for cerebrovascular disease at a young age.Semantic proximity Read ↗

The p22phox C242T gene polymorphism is associated with a reduced risk of angiographically verified coronary artery disease in a high-risk Finnish Caucasian population. The Finnish Cardiovascular Study.Semantic proximity Read ↗

The effect of p22-PHOX (CYBA) polymorphisms on premature coronary artery disease (≤ 40 years of age).Semantic proximity Read ↗

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