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Exploring the Wnt pathway-associated LncRNAs and genes involved in pancreatic carcinogenesis driven by Tp53 mutation.

Pharmaceutical research - 1 Mar 2015

Wang Qi, Jiang He, Ping Chen, Shen Ruizhe, Liu Tingting, Li Juanjuan, Qian Yuting, Tang Yanping, Cheng Shidan, Yao Weiyan, Wang Lifu

Abstract excerpt

PURPOSE: Study the contribution of long non-coding RNAs (lncRNAs) to progression of pancreatic intraepithelial neoplasia (PanIN) to pancreatic ductal adenocarcinoma (PDAC). METHODS: We explored lncRNAs profilings in PanIN cell line (SH-PAN) isolated from Pdx-1-Cre; LSL-Kras (G12D/+) mice and PDAC cell line (DT-PCa) isolated from Pdx-1-Cre; LSL- Kras (G12D/+) ; LSL- Tp53 (R172H/+) mice by lncRNAs microarray, and...

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Source

Identifiers

PMID: 24469904
DOI: 10.1007/s11095-013-1269-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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