Identifying and mapping cell-type-specific chromatin programming of gene expression.

Abstract excerpt

A problem of substantial interest is to systematically map variation in chromatin structure to gene-expression regulation across conditions, environments, or differentiated cell types. We developed and applied a quantitative framework for determining the existence, strength, and type of relationship between high-resolution chromatin structure in terms of DNaseI hypersensitivity and genome-wide gene-expression...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chromatin
• Share to Deoxyribonuclease I
• Share to Gene Expression Profiling