Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer.

doi:10.1073/pnas.1313580111

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Article

Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer.

Proceedings of the National Academy of Sciences of the United States of America - 11 Feb 2014

Morrison Carl D, Liu Pengyuan, Woloszynska-Read Anna, Zhang Jianmin, Luo Wei, Qin Maochun, Bshara Wiam, Conroy Jeffrey M, Sabatini Linda, Vedell Peter, Xiong Donghai, Liu Song, Wang Jianmin, Shen He, Li Yinwei, Omilian Angela R, Hill Annette, Head Karen, Guru Khurshid, Kunnev Dimiter, Leach Robert, Eng Kevin H, Darlak Christopher, Hoeflich Christopher, Veeranki Srividya, Glenn Sean, You Ming, Pruitt Steven C, Johnson Candace S, Trump Donald L

Abstract excerpt

Using complete genome analysis, we sequenced five bladder tumors accrued from patients with muscle-invasive transitional cell carcinoma of the urinary bladder (TCC-UB) and identified a spectrum of genomic aberrations. In three tumors, complex genotype changes were noted. All three had tumor prote...

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Identifiers

PMID: 24469795
DOI: 10.1073/pnas.1313580111
PMCID: PMC3926024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24469795-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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