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Article

A high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage response.

Oncogene - 1 Aug 2013

Schepeler T, Lamy P, Hvidberg V, Laurberg J R, Fristrup N, Reinert T, Bartkova J, Tropia L, Bartek J, Halazonetis T D, Pan C-C, Borre M, Dyrskjøt L, Orntoft T F

Abstract excerpt

One major challenge in cancer research is to understand the complex interplay between the DNA damage response (DDR), genomic integrity, and tumor development. To address these issues, we analyzed 43 bladder tumor genomes from 22 patients using single nucleotide polymorphism (SNP) arrays, and tissue expression of multiple DDR proteins, including Timeless and its interaction partner Tipin. The SNP profiles...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22926521
DOI: 10.1038/onc.2012.381

Genes

ATM
ATR
FGFR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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