Article
Genetic association of human leukocyte antigens with chronicity or resolution of hepatitis B infection in thai population.
PloS one - 1 Jan 2014
Posuwan Nawarat, Payungporn Sunchai, Tangkijvanich Pisit, Ogawa Shintaro, Murakami Shuko, Iijima Sayuki, Matsuura Kentaro, Shinkai Noboru, Watanabe Tsunamasa, Poovorawan Yong, Tanaka Yasuhito
Abstract excerpt
BACKGROUND: Previous studies showed that single nucleotide polymorphisms (SNPs) in the HLA-DP, TCF19 and EHMT2 genes may affect the chronic hepatitis B (CHB). To predict the degree of risk for chronicity of HBV, this study determined associations with these SNPs. METHODS: The participants for thi...
Topics
- Adult
- Aged
- Carcinoma, Hepatocellular
- Female
- Gene Frequency
- Genetic Association Studies
- HLA-DP alpha-Chains
- HLA-DP beta-Chains
- Hepatitis B, Chronic
- Histocompatibility Antigens
- Histone-Lysine N-Methyltransferase
- Humans
- Linkage Disequilibrium