Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic alterations are related to clinicopathological features and risk of recurrence/metastasis of hepatocellular carcinoma.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Sept 2025

Meng Lili, Jiang Zhenjian, Shen Guangyue, Lin Shulan, Gao Feng, Guo Xinxin, Lv Bin, Hu Shuying, Ni Zheng, Chen Shanghua, Ji Yuan

Abstract excerpt

Lack of efficient biomarkers and clinical translation of molecular typing impedes the implementation of targeted therapy for hepatocellular carcinoma (HCC). High-throughput sequencing techniques represented by next-generation sequencing (NGS) are tools for detecting targetable genes. The objective of this study is to explore the genetic alterations associated with clinicopathological features and the risk of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Copy Number Variations

Share to Follow-Up Studies

Share to Liver Neoplasms

Share to Liver Transplantation

Share to Neoplasm Recurrence, Local

Share to Tumor Suppressor Protein p53

Source

Open in PubMed Open full text

Identifiers

PMID: 39642087
DOI: 10.1097/CEJ.0000000000000939
PMCID: PMC12316113

Genes

CCND1
CTNNB1
TAF1
TP53
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic alterations are related to clinicopathological features and risk of recurrence/metastasis of hepatocellular carcinoma.PMID 39642087Read ↗

Molecular Scoring of Hepatocellular Carcinoma for Predicting Metastatic Recurrence and Requirements of Systemic ChemotherapySemantic proximity Read ↗

Genomic alterations in hepatocellular carcinoma patients undergoing liver transplantation predict recurrence and prognosisSemantic proximity Read ↗

Identification of a novel gene signature for the prediction of recurrence in HCC patients by machine learning of genome-wide databasesSemantic proximity Read ↗

Genomic landscape of Chinese patients with hepatocellular carcinoma using next-generation sequencing and its association with the prognosis.Semantic proximity Read ↗

Impact of Genomic Alterations on the Clinical Outcome of Patients With Hepatitis B-related Hepatocellular Carcinoma Receiving Curative Surgery: A Retrospective Cohort Study.Semantic proximity Read ↗

TERT-TP53 mutations: a novel biomarker pair for hepatocellular carcinoma recurrence and prognosisSemantic proximity Read ↗

Characterization of genomic alterations in Chinese colorectal cancer patients with liver metastases.Semantic proximity Read ↗

Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification.Semantic proximity Read ↗

Tumor Mutational Burden as a Prognostic Biomarker for Relapse-Free Survival in Hepatocellular Carcinoma: Insights from Long-Term Follow-UpSemantic proximity Read ↗

Mutation profile and its correlation with clinicopathology in Chinese hepatocellular carcinoma patientsSemantic proximity Read ↗

Transcriptome and Exome Analyses of Hepatocellular Carcinoma Reveal Patterns to Predict Cancer Recurrence in Liver Transplant PatientsSemantic proximity Read ↗

Advances in molecular classification and precision oncology in hepatocellular carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.