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Article

Interactions between mesenchymal stem cells, adipocytes, and osteoblasts in a 3D tri-culture model of hyperglycemic conditions in the bone marrow microenvironment.

Integrative biology : quantitative biosciences from nano to macro - 1 Mar 2014

Rinker Torri E, Hammoudi Taymour M, Kemp Melissa L, Lu Hang, Temenoff Johnna S

Abstract excerpt

Recent studies have found that uncontrolled diabetes and consequential hyperglycemic conditions can lead to an increased incidence of osteoporosis. Osteoblasts, adipocytes, and mesenchymal stem cells (MSCs) are all components of the bone marrow microenvironment and thus may have an effect on diabetes-related osteoporosis. However, few studies have investigated the influence of these three cell types on each...

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Source

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Identifiers

PMID: 24463781
DOI: 10.1039/c3ib40194d
PMCID: PMC3965183

Genes

MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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