Article
Validation of interleukin 28B genotyping assay for clinical use.
Clinical biochemistry - 1 Apr 2014
Cervinski Mark A, Sam Soya S, Steinmetz Heather B, Wood Brendan, Tsongalis Gregory J
Abstract excerpt
OBJECTIVES: The favorable CC genotype at rs12979860 upstream of the interleukin (IL)-28B gene is correlated with a greater post-treatment sustained virologic response rate in chronic hepatitis C infected patients. We report on our validation of a clinical genotyping assay for rs12979860 polymorphisms in the IL28B locus. DESIGN AND METHODS: The rs12979860 genotype was determined using a TaqMan® Real-Time PCR...
Read the complete abstract on PubMed