Article
Evaluation of peptide selection approaches for epitope-based vaccine design.
Tissue antigens - 1 Oct 2013
Schubert B, Lund O, Nielsen M
Abstract excerpt
A major challenge in epitope-based vaccine (EV) design stems from the vast genomic variation of pathogens and the diversity of the host cellular immune system. Several computational approaches have been published to assist the selection of potential T cell epitopes for EV design. So far, no thorough comparison between the current methods has been realized. Using human immunodeficiency virus as test case,...
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