Article
Selection-based design of in silico dengue epitope ensemble vaccines.
Chemical biology & drug design - 1 Jan 2019
Murphy David, Reche Pedro, Flower Darren R
Abstract excerpt
Dengue virus affects approximately 130 countries. Twenty-five percentage of infections result in febrile, self-limiting illness; heterotypic infection results in potentially fatal dengue haemorrhagic fever or dengue shock syndrome. Only one vaccine is currently available. Its efficacy is very variable. Thus, to target dengue, we used an innovative immunoinformatics protocol to design a putative epitope ensemble...
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