Article
Measuring midkine: the utility of midkine as a biomarker in cancer and other diseases.
British journal of pharmacology - 1 Jun 2014
Jones D R
Abstract excerpt
Midkine (MK) is a pleiotropic growth factor prominently expressed during embryogenesis but down-regulated to neglible levels in healthy adults. Many published studies have demonstrated striking MK overexpression compared with healthy controls in various pathologies, including ischaemia, inflammation, autoimmunity and, most notably, in many cancers. MK expression is detectable in biopsies of diseased, but not...
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