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Article

Abnormal expression, highly efficient detection and novel truncations of midkine in human tumors, cancers and cell lines.

Cancer letters - 8 Aug 2007

Tao Ping, Xu Donghui, Lin Shuibin, Ouyang Gao-Liang, Chang Youde, Chen Qin, Yuan Yuanyang, Zhuo Xinming, Luo Qicong, Li Jie, Li Baoan, Ruan Lingjuan, Li Qifu, Li Zhixing

Abstract excerpt

We detected aberrant Midkine (MK) expressions in human insulinoma and pancreatic cancer tissues by immunohistochemistry, revealing its potential role in tumorigenesis/carcinogenesis. With a nested-touchdown PCR program we were able to detect the tMK in all human tumor/cancer tissues and cancer/tumor cell lines. Detection of MK in the peripheral cells and precancerous lesions implies its potential for early...

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PMID: 17379400
DOI: 10.1016/j.canlet.2007.01.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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