Article
Pilot study of variants of the IL-23R and STAT3 genes reveals no association with Hashimoto's thyroiditis in the Croatian population.
Endocrine research - 1 Jan 2014
Stevic Mirjana Suver, Stefanic Mario, Tokic Stana, Glavas-Obrovac Ljubica, Mihaljevic Silvio, Karner Ivan
Abstract excerpt
Interleukin-23 receptor (IL-23R) and signal transducer and activator of transcription 3 (STAT3) polymorphisms are common risk factors for a number of T helper (Th) 17-mediated autoimmune diseases. However, the importance of genetic variations in Th17 pathways to thyroid autoimmunity, and particularly Hashimoto's thyroiditis (HT), is not fully understood. In this study, we genotyped three single nucleotide...
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