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The Link Between Periodontal Disease and Rheumatoid Arthritis: An Updated Review

23 Jan 2014

Abstract excerpt

Porphyromonas gingivalis is a leading pathogen in chronic periodontitis, a disease process involving progressive destruction of the tissues that support the teeth. Recently, the organism has been reported to produce a unique bacterial enzyme, P. gingivalis peptidyl-arginine deiminase (PPAD), which has the ability to convert arginine residues in proteins to citrulline. Protein citrullination alters protein...

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PMID: 24458478
DOI: 10.1007/s11926-014-0408-9

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