Article
Rheumatoid arthritis and periodontal disease.
Joint bone spine - 1 Dec 2010
Berthelot Jean-Marie, Le Goff Benoît
Abstract excerpt
The prevalence of periodontal disease has increased two-fold among patients with rheumatoid arthritis (RA) compared to the general population. This increased prevalence is unrelated to secondary Sjögren's syndrome but instead reflects shared pathogenic mechanisms, including an increased prevalence of the shared epitope HLA-DRB1-04; exacerbated T-cell responsiveness with high tissue levels of IL-17; exaggerated...
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