Are the SNPs of NKX2-1 associated with papillary thyroid carcinoma in the Han population of Northern China?

doi:10.1007/s11684-014-0310-x

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Are the SNPs of NKX2-1 associated with papillary thyroid carcinoma in the Han population of Northern China?

Frontiers of medicine - 1 Mar 2014

Ai Lizhe, Yu Yaqin, Liu Xiaoli, Wang Chong, Shi Jieping, Sun Hui, Yu Qiong

Abstract excerpt

Papillary thyroid carcinoma (PTC) is one of the most common tumors of the thyroid gland. The common risk factors of PTC include ionizing radiation, positive family history, and thyroid nodular disease. PTC was identified in Europeans by conducting a genome-wide association study, and a strong association signal with PTC was observed in rs944289 and NKX2-1 (located at the 14q13.3 locus), which was probably the...

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PMID: 24452548
DOI: 10.1007/s11684-014-0310-x

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