Article
Association between x-ray repair cross-complementing group 3 (XRCC3) genetic polymorphisms and papillary thyroid cancer susceptibility in a Chinese Han population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2016
Yuan Kai, Huo Meiling, Sun Yong, Wu Hongyan, Chen Hongqiang, Wang Yulong, Fu Rongzhan
Abstract excerpt
Papillary thyroid cancer (PTC) is a predominant type of thyroid cancer. Ionizing radiation is the only well-established risk factor and may result in double-strand breaks. The x-ray repair cross-complementing group 3 (XRCC3) gene plays a vital role in DNA repair through homologous recombination. We aimed at investigating the association between XRCC3 genetic polymorphisms and PTC susceptibility. Eighty-three PTC...
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